Abstract
Kinins are neuropeptides involved in the process of pain and inflammation. They are released through the activation of two receptors B1 and B2. The B2 receptor is considered a constitutive receptor in central and peripheral tissues and the B1 receptor is rarely expressed in normal tissues, but may be expressed after infection and tissue injury plasma leakage, cell migration, pain and hyperalgesia, although many studies have revealed the presence of this receptor constitutively in the canine cardiovascular system. Capsaicin is a vanilloid receptor type 1 (TRV1), a component of red pepper, participates in the thermal transduction of pain and inflammation. TRV1 causes degeneration of primary afferent fibers (C (Aδ)) which are sensory fibers that mediate pain.
References
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