Abstract
This study assessed community health workers' knowledge about HPV in primary health care in the southern region of São Paulo, identifying specific gaps and their association with sociodemographic and training characteristics. A cross-sectional study was conducted with 183 community health workers using an electronic questionnaire including sociodemographic and work variables and an HPV knowledge instrument. Descriptive statistics and Student's t-test were used, considering a 5% significance level. Participants showed a higher percentage of correct answers on general aspects of HPV, while gaps persisted in specific content, including condom effectiveness, natural history of infection, and vaccination schedule. These findings reinforce the need for continuing education for community health workers, with emphasis on technical-scientific content related to HPV prevention, vaccination, and transmission.
References
Kombe Kombe AJ, Li B, Zahid A, Mengist HM, Bounda GA, Zhou Y, et al. Epidemiology and burden of human papillomavirus and related diseases, molecular pathogenesis, and vaccine evaluation. Front Public Health. 2020;8:552028. https://doi.org/10.3389/fpubh.2020.552028
Williamson AL. Recent developments in human papillomavirus (HPV) vaccinology. Viruses. 2023;15(7):1441. https://doi.org/10.3390/v15071441
Instituto Nacional de Câncer (INCA). Estimativa 2023: incidência de câncer no Brasil [Internet]. Rio de Janeiro: INCA; 2023 [citado em 4 set 2026]. Disponível em: https://www.gov.br/inca/pt-br/assuntos/cancer/numeros/estimativa
Plotzker R, Vaidya A, Pokharel U, Stier E. Sexually transmitted human papillomavirus: update in epidemiology, prevention, and management. Infect Dis Clin North Am. 2023;37(2):289-310. https://doi.org/10.1016/j.idc.2023.02.006
Brasil. Ministério da Saúde. Secretaria de Atenção Primária à Saúde (SAPS). O que é a atenção primária [Internet]. Brasília: Ministério da Saúde; [data desconhecida] [citado em 4 set 2026]. Disponível em: https://www.gov.br/saude/pt-br/composicao/saps
Brasil. Ministério da Saúde. Departamento de HIV, Aids, Tuberculose e Hepatites Virais e Infecções Sexualmente Transmissíveis. HPV [Internet]. Brasília: Ministério da Saúde; [data desconhecida] [citado em 4 set 2026]. Disponível em: https://www.gov.br/aids/pt-br/assuntos/ist/hpv
Silva TL, Magalhães HLGO, Solá ACN, Rodrigues BC, Carneiro ACMO, Schechtman NP, et al. Capacitação do agente comunitário de saúde na prevenção do câncer de colo uterino. Rev Bras Educ Med. 2012;36(1):1-8.
Silva S, Bonfim E, Silva M, Souza N. Agente comunitário em saúde: o uso da educação em saúde como facilitadora do cuidado. Rev Em Extensão. 2015;13(2):122-8.
Sampaio GA. Agentes comunitários de saúde: considerações sobre desafios - realidades desses profissionais na realização de seu trabalho. Rev Foco. 2025;18(10):e7278. https://doi.org/10.54751/revistafoco.v18n10-021
Morosini MV, Fonseca AF. Os agentes comunitários na Atenção Primária à Saúde no Brasil: inventário de conquistas e desafios. Saude Debate. 2018;42(esp. 1):261-74. https://doi.org/10.1590/0103-11042018S117
Andrade CCB, Paschoalin HC, Sousa AI, Greco RM, Almeida GBS. Agentes comunitários de saúde: perfil sociodemográfico, condições laborais e hábitos de vida. Rev Enferm UFPE On Line. 2018;12(6):1648-56. https://doi.org/10.5205/1981-8963-v12i6a231436p1648-1656-2018
Méllo LMBD, Santos RCD, Albuquerque PCD. Agentes comunitárias de saúde: o que dizem os estudos internacionais? Cienc Saude Colet. 2023;28(4):1055-68. https://doi.org/10.1590/1413-81232023284.12982022
Almeida MCS, Baptista PCP, Silva A. Workloads and strain process in Community Health Agents. Rev Esc Enferm USP. 2016;50(1):93-100. https://doi.org/10.1590/S0080-623420160000100013
Grigolo AV, Wendt GW, Lucio LC. Correction: Factors associated with HPV knowledge among professionals in the city of Francisco Beltrão, Brazil. J Community Health. 2023;48(4):740. https://doi.org/10.1007/s10900-023-01221-9
Maynard G, Akpan IN, Meadows RJ, Fulda KG, Patel DA, Leidner V, et al. Evaluation of a human papillomavirus vaccination training implementation in clinical and community settings across different clinical roles. Transl Behav Med. 2024;14(4):249-56. https://doi.org/10.1093/tbm/ibae007
Cano-Caballero MG, Garrido Peña F, Gil García E, Cano-Caballero Gálvez MD. Opiniones de los profesionales sanitarios de Atención Primaria de Andalucía acerca del virus del papiloma humano y su vacuna. An Sist Sanit Navar. 2018;41(1):27-34. https://doi.org/10.23938/ASSN.0128
Osaghae I, Darkoh C, Chido-Amajuoyi OG, Chan W, Wermuth PP, Pande M, et al. Association of provider HPV vaccination training with provider assessment of HPV vaccination status and recommendation of HPV vaccination. Hum Vaccin Immunother. 2022;18(6):2132755. https://doi.org/10.1080/21645515.2022.2132755
Chen X, Xu T, Wu J, Sun C, Han X, Wang D, et al. Exploring factors influencing awareness and knowledge of human papillomavirus in Chinese college students: a cross-sectional study. Hum Vaccin Immunother. 2024;20(1):2388347. https://doi.org/10.1080/21645515.2024.2388347
Waller J, Ostini R, Marlow LA, McCaffery K, Zimet G. Validation of a measure of knowledge about human papillomavirus (HPV) using item response theory and classical test theory. Prev Med. 2013;56(1):35-40. https://doi.org/10.1016/j.ypmed.2012.10.017
Manoel AL, Rodrigues AB, Piva EZ, Warpechowski TP, Schuelter-Trevisol F. Evaluation of knowledge about the Human Papilloma Virus (HPV) and its vaccination among Community Health Agents in the municipality of Tubarão, Santa Catarina, Brazil, in 2014. Epidemiol Serv Saude. 2017;26(2):399-404. https://doi.org/10.5123/S1679-49742017000200016
Molokwu J, Penaranda E, Flores S, Shokar NK. Evaluation of the effect of a promotora-led educational intervention on cervical cancer and human papillomavirus knowledge among predominantly Hispanic primary care patients on the US-Mexico border. J Cancer Educ. 2016;31(4):742-8. https://doi.org/10.1007/s13187-015-0914-0
Alsulami FT. Exploring the impact of knowledge about the human papillomavirus and its vaccine on perceived benefits and barriers to human papillomavirus vaccination among adults in the Western Region of Saudi Arabia. Healthcare (Basel). 2024;12(14):1416. https://doi.org/10.3390/healthcare12141416
Mazzadi A, Paolino M, Arrossi S. HPV vaccine acceptability and knowledge among gynecologists in Argentina. Salud Publica Mex. 2012;54(5):515-22.
Tarwireyi F, Chirenje ZM, Rusakaniko S. Cancer of the cervix: knowledge, beliefs and screening behaviours of health workers in Mudzi District in Mashonaland East Province, Zimbabwe. Cent Afr J Med. 2003;49(7-8):83-6.
Brasil. Ministério da Saúde. Departamento de HIV, Aids, Tuberculose e Hepatites Virais e Infecções Sexualmente Transmissíveis. Nota Técnica nº 41/2024-CGICI/DPNI/SVSA/MS [Internet]. Brasília: Ministério da Saúde; 2024 [citado em 4 set 2026]. Disponível em: https://www.gov.br/saude/pt-br/centrais-de-conteudo/publicacoes/notas-tecnicas/2024/nota-tecnica-no-41-2024-cgici-dpni-svsa-ms
Silva LEL, Oliveira MLC, Galato D. Receptividade à vacina contra o papilomavírus humano: uma revisão sistemática. Rev Panam Salud Publica. 2019;43:e22. https://doi.org/10.26633/RPSP.2019.22
Burchell AN, Richardson H, Mahmud SM, Trottier H, Tellier PP, Hanley J, et al. Modeling the sexual transmissibility of human papillomavirus infection using stochastic computer simulation and empirical data from a cohort study of young women in Montreal, Canada. Am J Epidemiol. 2006;163(6):534-43. https://doi.org/10.1093/aje/kwj077

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