Resumo
Objetivou-se demonstrar as evidências disponíveis sobre ozonioterapia em pacientes com COVID-19 e sua aplicabilidade terapêutica por meio de protocolos hospitalares. Trata-se de uma revisão integrativa, realizada nas fontes de busca PubMed e LILACS, no período de 2011 a 2021. Foram identificados 87 artigos, mas, selecionados 11 artigos que se adequaram à temática estudada. A literatura estudada apontou que o ozônio exerce atividade antiviral por meio da inibição da replicação viral e da inativação direta dos vírus. Também é um adjuvante às drogas antivirais. O tratamento combinado com ozônio e os antivirais demonstrou redução da inflamação e dos danos pulmonares. As vias de administração do ozônio foram sistêmica (retal) e auto-hemoterapia. Conclusões: A ozonioterapia é uma terapia adjuvante ao tratamento com antivirais em pacientes COVID-19-positivos, além de ser viável economicamente e de fácil administração.
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